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'Cell Proliferation' in keywords Facet   Publication Year 1983  [X]
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1Author    Giuseppe Colacicco, A. Rthur, A. PillaRequires cookie*
 Title    Electromagnetic M odulation of Biological Processes: ATPase Function and D NA Production by Raji Cancer Cells in vitro  
 Abstract    Addition o f either ATP or ouabain to the culture m edium markedly depressed thym idine incorporation into D N A in Raji cells. The electrom agnetic field, pulsating at very low frequency, did not affect D N A synthesis in normal culture m edia nor did it alter its ouabain-inhibition, but it partially reversed the ATP-inhibition. In spite o f the presence o f ATP, ouabain prevented stimulation o f ATPase and D N A synthesis by the field. Although no m echanism is known for the action o f either ATP or the field, the results may be interpreted in light o f existing speculations. In the absence o f the field, external ATP may go into an ATP pool that either blocks ATPase or feeds adenyl cyclase, which hinders D N A synthesis. In contrast, the electrom agnetic field may either turn o ff adenyl cyclase or sim ply stim ulate the 
  Reference    Z. Naturforsch. 38c, 468—470 (1983); received N ovem ber 29 1982/M arch 16 1983 
  Published    1983 
  Keywords    Pulsating Electromagnetic Fields, M embrane Coupling, Plasma M embrane ATPases, D N A Synthesis, Cell Proliferation 
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 TEI-XML for    default:Reihe_C/38/ZNC-1983-38c-0468.pdf 
 Identifier    ZNC-1983-38c-0468 
 Volume    38