1 | Author | Jürgen Van Der Bosch, Heinz Maier | Requires cookie* |
Title | Density-Dependent Growth Inhibiting Interactions between 3T3 and SV40-3T3 Cells in Mixed Cultures ![]() | ||
Abstract | 3T3 cells are shown to reduce SV40-3T3 cell population growth in a density-dependent manner in co-cultures of 3T3 and SV40-3T3 cells. The development of this inhibitory activity roughly parallels the development of density-dependent inhibition of growth in homogeneous 3T3 control cultures. The extent of reduction of SV40-3T3 growth can be manipulated by pretreatment of 3T3 cells with a high serum concentration. SV40-3T3 growth rates are reduced by factors between 10 and 20 under optimum inhibitory conditions as compared to SV40-3T3 growth in control cultures. | ||
Reference | Z. Naturforsch. 34c, 272 (1979); received December 19 1978 | ||
Published | 1979 | ||
Keywords | 3T3 Cells, SV40-3T3 Cells, Growth Inhibition, Cell Interactions | ||
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