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'Cardenolide Sequestration' in keywords Facet   Publication Year 1995  [X]
Facet   section ZfN Section C  [X]
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1Author    A.Ndreas Detzel, Michael WinkRequires cookie*
 Title    Evidence for a Cardenolide Carrier in Oncopeltus fasciatus (Dallas) (Insecta: Hemiptera)  
 Abstract    O ncopeltus fasciatus (H emiptera) is morphologically and physiologically adapted to seques­ ter cardiac glycosides for its chemical defence against predators. A s a prerequisite for carde­ nolide utilization this bug has to take up and store the dietary cardenolides. Using isolated midguts it could be shown experimentally that the resorption of [3H]digoxin is time-, and temperature-dependent. The hydrogen ion concentration for uptake is optimal between pH 5.5 and 7 and an activation energy of 45 to 49 kJ/mol can be derived from an Arrhenius plot. U ptake can be inhibited competitively by the polar cardiac glycoside convallatoxin. Sulf-hydryl group reagents (N-ethylmaleimide), membrane destabilizing compounds and respira­ tory chain inhibitors reduce digoxin resorption, as do inhibitors of sugar transport (e.g., phlo-ridzin). The experimental data thus provide evidence for a cardenolide carrier in midgut cells o f O. fasciatus. 
  Reference    Z. Naturforsch. 50c, 127—134 (1995); received October 10/November 18 1994 
  Published    1995 
  Keywords    O ncopeltus fasciatus, Chemical Defence, Cardenolide Sequestration, Carrier-Mediated Uptake, Cardenolide Carrier 
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 TEI-XML for    default:Reihe_C/50/ZNC-1995-50c-0127.pdf 
 Identifier    ZNC-1995-50c-0127 
 Volume    50