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1995 (1)
1Author    Kirsten Lorenzena, TimmA. Nkea, Silvia Konetschny-Rappb, Werner ScheuerbRequires cookie*
 Title    5-Hydroxy-3-vinyl-2(5H)-furanone -a New Inhibitor of Human Synovial Phospholipase A 2 and Platelet Aggregation from Fermentations of a C alyptella Species (Basidiomycetes)  
 Abstract    5-Hydroxy-3-vinyl-2(5H)-furanone, a potent and selective inhibitor of human synovial phospholipase A 2 was isolated from fermentations of a Calyptella species. Its structure as identified by spectroscopic methods is identical to PA 147, an antibiotic previously isolated from a streptomycete. 5-hydroxy-3-vinyl-2(5H)-furanone inhibits the aggregation of human and bovine platelets stimulated by different inducers and exhibits weak antimicrobial activities. 
  Reference    Z. Naturforsch. 50c, 403—409 (1995); received January 16/February 10 1995 
  Published    1995 
  Keywords    Basidiomycetes, Calyptella Species, Platelet Aggregation, Antibiotics, Phospholipase A 2 
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 TEI-XML for    default:Reihe_C/50/ZNC-1995-50c-0403.pdf 
 Identifier    ZNC-1995-50c-0403 
 Volume    50