| | 1 | Author
| Kirsten Lorenzena, TimmA. Nkea, Silvia Konetschny-Rappb, Werner Scheuerb | Requires cookie* | | | Title
| 5-Hydroxy-3-vinyl-2(5H)-furanone -a New Inhibitor of Human Synovial Phospholipase A 2 and Platelet Aggregation from Fermentations of a C alyptella Species (Basidiomycetes)  | | | | Abstract
| 5-Hydroxy-3-vinyl-2(5H)-furanone, a potent and selective inhibitor of human synovial phospholipase A 2 was isolated from fermentations of a Calyptella species. Its structure as identified by spectroscopic methods is identical to PA 147, an antibiotic previously isolated from a streptomycete. 5-hydroxy-3-vinyl-2(5H)-furanone inhibits the aggregation of human and bovine platelets stimulated by different inducers and exhibits weak antimicrobial activities. | | | |
Reference
| Z. Naturforsch. 50c, 403—409 (1995); received January 16/February 10 1995 | | | |
Published
| 1995 | | | |
Keywords
| Basidiomycetes, Calyptella Species, Platelet Aggregation, Antibiotics, Phospholipase A 2 | | | |
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| default:Reihe_C/50/ZNC-1995-50c-0403.pdf | | | | Identifier
| ZNC-1995-50c-0403 | | | | Volume
| 50 | |
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