ZfN: Search Results

1	Author	Nazmi Abd, Elatife Kassab, Sanaa Osman Abdallah, Hamed Abdel, Reheem Ead, Doreya Zaki	Requires cookie*
	Title	Some New Tetrahydrothiopyrano[2,3-d]thiazole-2-thione Derivatives and their Biological Activities 3-Phenyl-2,4
	Reference	(Z. Naturforsch. 31b, 376—379 [1976]; received August 14 1975)
	Published	1976
	Keywords	thiazolidinedithiones, 1, 4-Cycloaddition, Heterodienes, Synthesis, Biological Activities
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	TEI-XML for	default:Reihe_B/31/ZNB-1976-31b-0376.pdf
	Identifier	ZNB-1976-31b-0376
	Volume	31

2	Author	F. I. Abdel-Hay, M. A. Omara, A. A. El-Barbary, M. El-Badawi	Requires cookie*
	Title	Organophosphorus Compounds of Expected Biological Activity, Part II* Preparation of Thiourea Derivatives and N-Aryl-phosphorothiomonoamidates
	Abstract	The examples of cyclodiphosphazanes so far studied do not contain any nuclei of biological interest [1]. In the present investigation we aimed to introduce ethyl p-amino-benzoate, 2-aminopyridine residues in the phosphazane molecule. For this purpose phos-phorus pentachloride was treated with ethyl p-aminobenzoate, p-anisidine, 2-amino-pyridine and 5-aminoquinoline to give l,3-di-j9-ethoxycarbonylphenyl-, l,3-di-j9-methoxy-phenyl-, l,3-di-2-pyridyl-and l,3-di-5-quinolinyl-2,2,2,4,4,4-hexachlorocyclo-diphos-phazane (la-d), respectively. The compounds la-d were treated with potassium thio-cyanate in acetone. The oily products formed were then treated with p-anisidine, ethyl-p-aminobenzoate and 2-aminopyridine whereupon solid products (2a-h) were obtained. The reaction probably takes place according to the following mechanism [2]. la: b: c: d: Ar 1 Ar C2H5OOCC6H4-(p) CH3OC6H4-(p) C5H4N-(2) C9H6N-(5) Ar Cl /N Cl ci >0< ci SCN NCS 2a: b: c:
	Reference	Z. Naturforsch. 34b, 297—299 (1979); received October 16 1978
	Published	1979
	Keywords	Organophosphorus Compounds, Thiourea Derivatives, Biological Activity
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	TEI-XML for	default:Reihe_B/34/ZNB-1979-34b-0297.pdf
	Identifier	ZNB-1979-34b-0297
	Volume	34

3	Author	Hans Moser, Grety Rihs, Hanspeter Sauter, Entwicklung Forschung, Pflanzenschutz	Requires cookie*
	Title	Der Einfluß yon Atropisomerie und chiralem Zentrum auf die biologische Aktivität des Metolachlor The Influence of Atropisomerism and Chiral Centre on the Biological Activity of Metolachlor
	Abstract	The four stereoisomers of the grass herbicide Metolachlor, the isomerism of which is based on a combination of a chiral centre and a chiral axis, were prepared, and their absolute configurations determined by X-ray analysis. The synthesis was achieved by using optically active starting materials and new optically active carbamates as intermediates. The herbicidal activity is mainly influenced by the chiral centre, the S-isomers being the most active ones.
	Reference	Z. Naturforsch. 37b, 451—462 (1982); eingegangen am 20. August 1981
	Published	1982
	Keywords	Chloro-acetanilide, Metolachlor, Atropisomerism, Chiral Centre, Biological Activity
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	TEI-XML for	default:Reihe_B/37/ZNB-1982-37b-0451.pdf
	Identifier	ZNB-1982-37b-0451
	Volume	37

4	Author	R. Tacke, M. Strecker, W. S. Sheldrick, E. Heeg, B. Berndt, K. M. Knapstein	Requires cookie*
	Title	Sila-Pharmaka, 14. Mitt. [1] Darstellung und Eigenschaften sowie Kristall-und Molekülstruktur von Sila-Difenidol Sila-Drugs, 14 th Communication [1] Preparation and Properties as well as Crystal and Molecular Structure of Sila-Difenidol
	Abstract	Sila-difenidol (6 b), a sila-analogue of the drug difenidol (6 a), was synthesized according to Scheme 1. 6 b and its new precursors 3 and 5 were characterized by their physical and chemical properties, and their structures confirmed by elementary analyses, *H NMR and mass spectroscopy. 6 b crystallizes orthorhombic P 2i 2i 2i with a — 11.523(1), b = 14.366(4), c = 11.450(1) A, Z = 4, Dber = 1.14 gcm-3. The structure was refined to fi = 0.050 for 1897 reflexions. A strong nearly linear intramolecular 0-H---N hydrogen bond of 2.685 A is observed. The anticholinergic, histaminolytic and musculotropic spasmolytic activities of 6 a and 6 b are reported.
	Reference	Z. Naturforsch. 34b, 1279—1285 (1979); eingegangen am 16. März 1979
	Published	1979
	Keywords	Sila-Difenidol, Syntheses, Crystal Structure, Molecular Structure, Biological Activity
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	TEI-XML for	default:Reihe_B/34/ZNB-1979-34b-1279.pdf
	Identifier	ZNB-1979-34b-1279
	Volume	34