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'Biological Activities' in keywords Facet   section ZfN Section C  [X]
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1977[X]
1Author    AngelM. RelimpioRequires cookie*
 Title    Structure and Anticholinesterase Activity of Series of Ethyl Substituted Phenyl Methylphosphonates  
 Abstract    Thirty derivates from substituted-phenyl-ethyl methylphosphonates have been synthesized and their inhibiting power of acetyl-cholinesterase have been examined in vitro and in vivo. The cor­ relation between inhibition of the enzyme and electrophylic power of the substituent of the phenyl group was excellent, but when this group contains two substituents, steric factors appear to operate. The activity of these compounds has been demonstrated to be higher than their phosphate analogs. 
  Reference    (Z. Naturforsch. 32c, 760 [1977]; received June 13 1977) 
  Published    1977 
  Keywords    Cholinesterase, Methylphosphonates, Inhibitors, Biological Activity 
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 TEI-XML for    default:Reihe_C/32/ZNC-1977-32c-0760.pdf 
 Identifier    ZNC-1977-32c-0760 
 Volume    32