| 1 | Author
| Kirsten Lorenzen, Timm Anke, Uwe Anders, H. Erm An Hindermayr, Fritz Hansske | Requires cookie* | | Title
| Two Inhibitors of Platelet Aggregation from a Panus Species (Basidiomycetes)  | | | Abstract
| Two inhibitors of platelet aggregation were isolated from fermentations of Panus sp. 9096. One inhibitor proved to be identical to naematolon (2), an antibiotic previously isolated by S. Backens et al. from several Hypholoma species. The other metabolite, panudial (1), is a new nordrimane (cw-annelation of the bicyclus) lacking the carbon atom in position 10 of the drimane skeleton. Panudial is a potent inhibitor of bovine and human platelet aggregation stimulated by different inducers. | | |
Reference
| Z. Naturforsch. 49c, 132—138 (1994); received September 1/ | | |
Published
| 1994 | | |
Keywords
| Basidiomycetes, Lentineae, Panus Species, Platelet Aggregation, Antibiotics, Drimanes | | |
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| | | | TEI-XML for
| default:Reihe_C/49/ZNC-1994-49c-0132.pdf | | | Identifier
| ZNC-1994-49c-0132 | | | Volume
| 49 | |
2 | Author
| K. Irsten Lorenzen, Tim, H. Erm, H. Inderm Ayr, F. Ritz Hansske | Requires cookie* | | Title
| 4-Epidihydrocochlioquinone B and 14-Epicochlioqumone B, Antibiotics from Fermentations of the Ascomycete Neobulgaria pur a: Structure Elucidation and Effects on Platelet Aggregation  | | | Abstract
| 14-Epicochlioquinone B (1) and 14-epidihydrocochlioquinone B (2) were isolated from sub merged cultures of Neobulgaria pura (Pers. ex Fr.) Petrak. 14-Epicochlioquinone B is a potent inhibitor of hum an and bovine platelet aggregation stimulated by different inducers. 14-Epidihydrocochlioquinone B does not inhibit the aggregation of platelets. In addition, both 1 and 2 exhibited cytotoxic and antimicrobial activites. | | |
Reference
| Z. Naturforsch. 49c, 312—320 (1994); received September 9 1993/ | | |
Published
| 1994 | | |
Keywords
| Ascomycetes, Helotiales, Platelet Aggregation, Antibiotics, Cochlioquinones | | |
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| default:Reihe_C/49/ZNC-1994-49c-0312.pdf | | | Identifier
| ZNC-1994-49c-0312 | | | Volume
| 49 | |
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