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'Antibiotic' in keywords Facet section ZfN Section C [X]

Results 14 Items

1	Author	K. Eisele	Requires cookie*
	Title	Sequence Variation on an Antibiotically Active Tripeptide Seven tripeptides with the sequence L-Arg-D,L-X-L-Phe were synthesised. Three of these peptides showed anti- biotical activity on fungi. The amino-and the carboxylic terminus of the peptide L-Arg-D,L-Phe-L-Phe, which showed antibiotical activity, were changed to give the sequences L-X-D,L-Phe-L-Phe or L-Arg-D,L-Phe-L-X respectively
	Abstract	The resulting tripeptides showed no antibiotical activity.
	Reference	(Z. Naturforsch. 30c, 541 [1975]; eingegangen am 11. Februar/3. April 1975)
	Published	1975
	Keywords	Antibiotics, Sequence Variation, Peptide Synthesis
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	TEI-XML for	default:Reihe_C/30/ZNC-1975-30c-0541_n.pdf
	Identifier	ZNC-1975-30c-0541_n
	Volume	30

2	Author	R. Kanne, H. Zähner	Requires cookie*
	Title	Concentrations of W ild -T y p e and a Macrotetrolide Negative Mutant of Streptomyces griseus
	Abstract	The studied macrotetrolide negative mutant of Streptomyces griseus showed a different spe cificity of potassium accumulation than the macrotetrolide producing wild-type, indicating, that the macrotetrolides may be part of the physiological potassium carrier.
	Reference	(Z. Naturforsch. 31c, 115 [1976]; received November 3 1975)
	Published	1976
	Keywords	Potassium Sodium, Ionophores, Antibiotics, Transport
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	TEI-XML for	default:Reihe_C/31/ZNC-1976-31c-0115.pdf
	Identifier	ZNC-1976-31c-0115
	Volume	31

3	Author	Bernd Schulz-Harder, Ernst-Randolf Lochmann	Requires cookie*
	Title	Initiation in einem Polyribosomen-abhängigen Protein-synthetisierenden zellfreien System aus Saccharomyces Initiation in a Polyribosome-Dependent Protein-Synthesizing Cell-Free System from Saccharomyces
	Abstract	A method to prepare polyribosomes from yeasts by using the french-press is described. The highest yield of polyribosomes was derived from late log-phase cells. These polyribosomes, in cubated in a cell-free system, were able to reinitiate protein synthesis, which was shown by in hibiting aminoacid incorporation by aurintricarboxylic acid, edeine and sodiumfluoride. W e de veloped the translational system in order to look for the optimal ion-conditions of a DNA-dependent protein-synthesizing system. W e found out that at the optimal MgCL-concentration (6 mM) protein synthesis was strongly inhibited by Mangan ions which are required for transcription in yeast. If protein-synthesis was carried out with 2 mM and 3 mM M gCU maximal aminoacid incorporation was observed at 2 mM and 1.5 mM M nCl2 .
	Reference	(Z. Naturforsch. 31c, 169 [1976]; eingegangen am 10. November 1975)
	Published	1976
	Keywords	Yeast, Polyribosomes, Cell-Free Protein Synthesis, Antibiotics, Ion-Conditions
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	TEI-XML for	default:Reihe_C/31/ZNC-1976-31c-0169.pdf
	Identifier	ZNC-1976-31c-0169
	Volume	31

4	Author	R. Einhard Kanne	Requires cookie*
	Title	Isolation and Characterization of a Potassium Specific Ionophore from Streptococcus fuecalis
	Abstract	The synthesis of a potassium and rubidium specific ionophore by S treptococcu s faecalis has been proved, using bilayer measurements. The characteristics of this substance agree with the ones, published for free mobile carriers, such as valinomycin and the macrotetrolides.
	Reference	(Z. Naturforsch. 32c, 926 [1977]; received August 24 1977)
	Published	1977
	Keywords	Potassium, Ionophores, Transport, Antibiotics, Black Lipid Membranes
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	TEI-XML for	default:Reihe_C/32/ZNC-1977-32c-0926.pdf
	Identifier	ZNC-1977-32c-0926
	Volume	32

5	Author	Ute Laudenbach, Jürgen Kesselmeier	Requires cookie*
	Title	Some Observations on the Saponin Accumulation in Oat Seedlings and on the Transformation of the Avenacosides to the Antibiotic 26-Desgluco-avenacosides
	Abstract	The accumulation o f the steroidal saponins avenacoside A and B in oat was investigated in green and etiolated seedlings and was found to be strictly bound to the growth o f the seedlings. N o significant differences were detected between green and etiolated seedlings, showing that there is no relation between saponin accumulation and plastid developm ent. As the role o f the oat saponins has to be seen as a protective device against fungi and bacteria, the transformation o f the inactive avenacosides to their corresponding antibiotic 26-desgluco-avenacosides was tested in dependence o f pH and temperature. During disruption o f leaves, transformation occurs almost com pletely over a wide pH-range (pH 4 —pH 10); the degree o f transformation exhibits no distinct temperature optimum but a drastic decrease at 70 °C.
	Reference	Z. Naturforsch. 37c, 1095 (1982); received July 10 1982
	Published	1982
	Keywords	Saponin Accumulation, Antibiotic, /?-Glucosidase, Oat
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	TEI-XML for	default:Reihe_C/37/ZNC-1982-37c-1095.pdf
	Identifier	ZNC-1982-37c-1095
	Volume	37

6	Author	A. Stärk, T. Anke, A. Kirfel, G. Will	Requires cookie*
	Title	Lentinellic Acid, a Biologically Active Protoilludane Derivative from Lentinellus Species (Basidiomycetes) [1]
	Abstract	A new antimicrobial and cytotoxic sesquiterpenoid, lentinellic acid (1), has been isolated from submerged cultures of Lentinellus ursinus and L. omphalodes. The structure of the antibiotic was elucidated by spectroscopic methods and a single crystal X-ray analysis. 1 may be formed biogenetically by condensation of a protoilludane aldehyde 4 with a malonate unit.
	Reference	Z. Naturforsch. 43c, 177—183 (1988); received October 16 1987
	Published	1988
	Keywords	Lentinellus, Basidiomycetes, Sesquiterpenoids, Protoilludanes, Lentinellic Acid, Antibiotics
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	TEI-XML for	default:Reihe_C/43/ZNC-1988-43c-0177.pdf
	Identifier	ZNC-1988-43c-0177
	Volume	43

7	Author	Andreas Stärk, Timm Anke, Ursula Mocek, Wolfgang Steglich	Requires cookie*
	Title	Omphalone, an Antibiotically Active Benzoquinone Derivative from Fermentations of Lentinellus omphalodes [1]
	Abstract	Om phalone, a new antibiotic, cytotoxic, and phytotoxic pigment has been isolated from fer mentations o f a Canadian strain of Lentinellus omphalodes. Its structure has been established as 2-(4-methylfuran-2-yl)-l,4-benzoquinone (1) by spectroscopic investigations and conver sion into leuco-acetate 2.
	Reference	Z. Naturforsch. 46c, 989—992 (1991); received February 6/July 20 1991
	Published	1991
	Keywords	Om phalone, Benzoquinone Derivative, Antibiotic, Lentinellus omphalodes, Basidiomycete
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	TEI-XML for	default:Reihe_C/46/ZNC-1991-46c-0989.pdf
	Identifier	ZNC-1991-46c-0989
	Volume	46

8	Author	JoH. An, N. Es, D. Asen, Ro Ck, W. Olfgang Steglich	Requires cookie*
	Title	Phellodonic Acid, a New Biologically Active Hirsutane Derivative from Phellodon melaleucus (Thelephoraceae, Basidiomycetes) [1]
	Abstract	A new hirsutane derivative, phellodonic acid (1), has been isolated from fermentations of Phellodon melaleucus strain 87113. Its structure was elucidated by spectroscopic methods. The compound exhibits antibiotic activities towards bacteria and fungi. 1 is the first bioactive metabolite from cultures of a species belonging to the family Thelephoraceae.
	Reference	Z. Naturforsch. 48c, 545—549 (1993); received April 23 1993
	Published	1993
	Keywords	Phellodon melaleucus, Sesquiterpenoids, Hirsutane, Phellodonic Acid, Antibiotic
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	TEI-XML for	default:Reihe_C/48/ZNC-1993-48c-0545.pdf
	Identifier	ZNC-1993-48c-0545
	Volume	48

9	Author	Kirsten Lorenzen, Timm Anke, Uwe Anders, H. Erm An Hindermayr, Fritz Hansske	Requires cookie*
	Title	Two Inhibitors of Platelet Aggregation from a Panus Species (Basidiomycetes)
	Abstract	Two inhibitors of platelet aggregation were isolated from fermentations of Panus sp. 9096. One inhibitor proved to be identical to naematolon (2), an antibiotic previously isolated by S. Backens et al. from several Hypholoma species. The other metabolite, panudial (1), is a new nordrimane (cw-annelation of the bicyclus) lacking the carbon atom in position 10 of the drimane skeleton. Panudial is a potent inhibitor of bovine and human platelet aggregation stimulated by different inducers.
	Reference	Z. Naturforsch. 49c, 132—138 (1994); received September 1/
	Published	1994
	Keywords	Basidiomycetes, Lentineae, Panus Species, Platelet Aggregation, Antibiotics, Drimanes
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	TEI-XML for	default:Reihe_C/49/ZNC-1994-49c-0132.pdf
	Identifier	ZNC-1994-49c-0132
	Volume	49

10	Author	K. Irsten Lorenzen, Tim, H. Erm, H. Inderm Ayr, F. Ritz Hansske	Requires cookie*
	Title	4-Epidihydrocochlioquinone B and 14-Epicochlioqumone B, Antibiotics from Fermentations of the Ascomycete Neobulgaria pur a: Structure Elucidation and Effects on Platelet Aggregation
	Abstract	14-Epicochlioquinone B (1) and 14-epidihydrocochlioquinone B (2) were isolated from sub merged cultures of Neobulgaria pura (Pers. ex Fr.) Petrak. 14-Epicochlioquinone B is a potent inhibitor of hum an and bovine platelet aggregation stimulated by different inducers. 14-Epidihydrocochlioquinone B does not inhibit the aggregation of platelets. In addition, both 1 and 2 exhibited cytotoxic and antimicrobial activites.
	Reference	Z. Naturforsch. 49c, 312—320 (1994); received September 9 1993/
	Published	1994
	Keywords	Ascomycetes, Helotiales, Platelet Aggregation, Antibiotics, Cochlioquinones
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	TEI-XML for	default:Reihe_C/49/ZNC-1994-49c-0312.pdf
	Identifier	ZNC-1994-49c-0312
	Volume	49

11	Author	Brigitte Simona, Timm Anke3, U. Andersb, M. Neuhausb, F. Hansskeb	Requires cookie*
	Title	Collybial, a New Antibiotic Sesquiterpenoid from Collybia confluens (Basidiomycetes)
	Abstract	A new antibiotic was isolated from fermentations of an american strain of Collybia con fluens. Its structure was elucidated by spectroscopic methods as 2,10,10-trim ethal-4-oxo-tri-cyclo[7.2.0.025]undec-6-en-carbaldehyde (with the relative stereo chemistry IS, 2 R. 5 R. 9 R) (1). The inhibitor, which was named collybial, is structurally related to koraiol, a sesquiter penoid isolated from Pinus koraiensis (Khan V. A . (1979), Khim. Prir. Soedin 5, 6 5 2 -6 5 8). Collybial inhibited the growth of Gram-positive bacteria at concentrations starting from 21.5 \| i m . The propagation of vesicular stomatitis virus (V SV) in baby hamster kidney (B H K -21) cells was inhibited by 21.5 [.i m collybial. Cytotoxic effects on B H K cells were observed at 5 fold higher concentrations.
	Reference	Z. Naturforsch. 50c, 173 (1995); received O ctober 12/Novem ber 11 1994
	Published	1995
	Keywords	Collybia confluens, Basidiomycetes, Antibiotic, Antiviral, Cytotoxic Activity
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	TEI-XML for	default:Reihe_C/50/ZNC-1995-50c-0173.pdf
	Identifier	ZNC-1995-50c-0173
	Volume	50

12	Author	Manfred Schnarr, MichaelM. Atthies, Wolfgang Lohmann	Requires cookie*
	Title	The Influence of Different Solvents on the Interaction between Metal Ions and Tetracycline
	Abstract	The interaction o f the antibiotic tetracycline with a few metal ions, esp. Cu(II), in different so l vents has been investigated by means o f IR, ESR, and U V /V IS spectroscopy. It could be shown that the site o f com plexation depends on the solvent used. In DM SO the interaction occurs mainly via the A ring. In water (pH = 5.7) and octanol, the A chrom ophore as well as the BCD entity o f the m olecule are involved in com plexation. If the tetracycline concentration exceeds the Cu(II) concentration, a 2 : 1 (antibiotic : Cu(II)) com plex seems to be formed, at least in DM SO.
	Reference	Z. Naturforsch. 34c, 1156 (1979); received June 25 1979
	Published	1979
	Keywords	Tetracycline, Antibiotics, Metal Ions, Com plexation, O ptical Absorption
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	TEI-XML for	default:Reihe_C/34/ZNC-1979-34c-1156.pdf
	Identifier	ZNC-1979-34c-1156
	Volume	34

13	Author	H. Eidrun, A. Nke, E. Lisabeth, H. Illen, -. M. Aske, W. Olfgang Steglich	Requires cookie*
	Title	9 ß-Hydroxymarasmic Acid and Other Sesquiterpenoids from Submerged Cultures of a Basidiomycete [1]
	Abstract	9 ß-Hydroxymarasmic acid, a new sesquiterpenoid, marasmic acid and isovelleral were isolated from cultures of a basidiomycete. Comparison of the antimicrobial activity of the three natural compounds together with two n-butyl ether derivatives of marasmic acid revealed MICs against bacteria in the range of 0 .2 —20 ng/ml. The antifungal, cytotoxic and phytotoxic activities of isovelleral were similar to those exhibited by marasmic acid, whereas the marasmic acid deriva tives were considerably less active than the parent compound. Isovelleral was the only compound to show hemolytic activity.
	Reference	Z. Naturforsch. 44c, 1 (1989); received August 31 1988
	Published	1989
	Keywords	Marasmic Acid, 9 ß-Hydroxymarasmic Acid, Isovelleral, Sesquiterpenoids, Antibiotics, Basidiomycetes
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	TEI-XML for	default:Reihe_C/44/ZNC-1989-44c-0001.pdf
	Identifier	ZNC-1989-44c-0001
	Volume	44

14	Author	Kirsten Lorenzena, TimmA. Nkea, Silvia Konetschny-Rappb, Werner Scheuerb	Requires cookie*
	Title	5-Hydroxy-3-vinyl-2(5H)-furanone -a New Inhibitor of Human Synovial Phospholipase A 2 and Platelet Aggregation from Fermentations of a C alyptella Species (Basidiomycetes)
	Abstract	5-Hydroxy-3-vinyl-2(5H)-furanone, a potent and selective inhibitor of human synovial phospholipase A 2 was isolated from fermentations of a Calyptella species. Its structure as identified by spectroscopic methods is identical to PA 147, an antibiotic previously isolated from a streptomycete. 5-hydroxy-3-vinyl-2(5H)-furanone inhibits the aggregation of human and bovine platelets stimulated by different inducers and exhibits weak antimicrobial activities.
	Reference	Z. Naturforsch. 50c, 403—409 (1995); received January 16/February 10 1995
	Published	1995
	Keywords	Basidiomycetes, Calyptella Species, Platelet Aggregation, Antibiotics, Phospholipase A 2
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	TEI-XML for	default:Reihe_C/50/ZNC-1995-50c-0403.pdf
	Identifier	ZNC-1995-50c-0403
	Volume	50