| 1 | Author | Sigurd Elz, Martin Dräger, Walter Schunack | Requires cookie* |
| Title | Synthese und absolute Konfiguration kettenverzweigter, Cimetidin-analoger Thioether Synthesis and Absolute Configuration of Chain Branched Cimetidine Analogous Thioethers  | ||
| Abstract | Chain branched Cimetidine analogous thioethers. promising building blocks for the preparation of H : -histaminergic compounds, were svnthetized from chiral aminoalkanethiols. Enantiomeri-callv pure amino acids or aminoalcohols were used as starting materials. In one case, a resolution via neutral and acid di-0-(4-toluoyl)tartrates was achieved in good yields and satisfying enan-tiomeric excess. The absolute configuration of an ethyl branched compound was determined using X-ray diffraction and anomalous dispersion. | ||
| Reference | Z. Naturforsch. 42b, 348—354 (1987); eingegangen am 22. September 1986 | ||
| Published | 1987 | ||
| Keywords | Aminoalkanethiols, Cimetidine, Crystal Structure, Histamine H : -Receptor Impromidine | ||
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