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'Amino acids' in keywords Facet   section ZfN Section C  [X]
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1Author    N. N. Osborne, V. Neuhoff, B. E. LeonardRequires cookie*
 Title      
 Abstract    The effects of a number of phenylethylamines on the metabolism of brain biogenic amines have been studied with the aim of differentiating neurochemi-cally between those drugs having a stimulant profile from those which are hallucinogenic 1_5. The pre­ sent study was undertaken to see if some of these drugs had a similar effect on the metabolism of serotonin in the oesophageal ganglia of the snail so that an assessment could be made of the possible usefulness of this in vitro preparation in the initial 
  Reference    (Z. Naturforsch. 29c, 189 [1974]; received December 12. 1973) 
  Published    1974 
  Keywords    Amphetamine, Amino Acids, Serotonin, Helix pomatia 
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 TEI-XML for    default:Reihe_C/29/ZNC-1974-29c-0189_n.pdf 
 Identifier    ZNC-1974-29c-0189_n 
 Volume    29 
2Author    Vera Jakubick, Henry DelincéeRequires cookie*
 Title    Strahleninduzierte Aggregatbildung von Proteinen: Bindung von Aminosäuren an Myoglobin Radiation-Induced Aggregation of Proteins: Binding of Amino Acids to Myoglobin  
 Abstract    When myoglobin is irradiated in the presence of amino acids, the most radiation-reactive species, like the aromatic and sulfur-containing amino acids, will bind preferentially to the protein. The radiation-induced binding is strongly dependent on the concentration of protein and amino acid. Subsequent to irradiation of myoglobin in the presence of radioactively labelled tryptophan followed by tryptic hydrolysis, only a single radioactive spot was detected on the fingerprint. The binding of amino acids is thus not randomly distributed over the protein molecule but occurs at specific reactive sites. 
  Reference    Z. Naturforsch. 33c, 203—209 (1978); eingegangen am 23. September 1977/27. Januar 1978 
  Published    1978 
  Keywords    Irradiation, Protein Aggregation, Myoglobin, Amino Acids, Specific Binding 
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 TEI-XML for    default:Reihe_C/33/ZNC-1978-33c-0203.pdf 
 Identifier    ZNC-1978-33c-0203 
 Volume    33 
3Author    BenjaminF. Matthews, JackM W IdholmRequires cookie*
 Title    Expression of Aspartokinase, Dihydrodipicolinic Acid Synthase and Homoserine Dehydrogenase During Growth of Carrot Cell Suspension Cultures on Lysine-and Threonine-Supplemented Media  
 Abstract    Reduction in the amounts o f activity o f the first enzyme, aspartokinase (EC 2.7.2.4) and two branch-point enzymes, dihydrodipicolinic acid synthase (EC 4.2.1.52) and homoserine dehydrogen­ ase (EC 1.1.1.3), located in the pathway for the synthesis o f aspartate-fam ily am ino acids, oc­ curred when cell suspension cultures of Daucus carota L. var. Danvers were grown in media contain­ ing 2 m M threonine or 2 m M lysine, endproducts of the pathway. Activity o f the lysine-sensitive form of aspartokinase was decreased when cells were grown in medium containing lysine and the ac­ tivity of the threonine-sensitive form was decreased when cells were grown in m edium containing threonine. Activity o f the branch-point enzyme leading to threonine synthesis, hom oserine dehy­ drogenase, was decreased up to 70% in specific activity (units/m g protein) and relative activity (units/g fresh weight) when cells were grown in m edia containing lysine or threonine. Threonine had no effect on the relative activity of dihydrodipicolinic acid synthase, but decreased its specific activity. Lysine decreased the relative activity of the synthase by up to 40%, but had little effect on its specific activity. The decreased activities o f the enzymes were apparently not due to binding of the inhibitory amino acids to the enzymes since homogenization of cells in buffer with 2 m M lysi­ ne and threonine did not decrease the m easurable enzyme activities. These and other results pres­ ented suggest that both forms of the aspartokinase activity and homoserine dehydrogenase activi­ ty can be altered by supplementing the growth medium with lysine or threonine. 
  Reference    Z. Naturforsch. 34c, 1177—1185 (1979); received June 18 1979 
  Published    1979 
  Keywords    Daucus carota, Suspension Cultures, Amino Acids, Enzyme Regulation 
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 TEI-XML for    default:Reihe_C/34/ZNC-1979-34c-1177.pdf 
 Identifier    ZNC-1979-34c-1177 
 Volume    34 
4Author    Qamar Khalid, M.Ataur RahmanRequires cookie*
 Title    Studies on Synergism between Glucose and Amino Acids with Respect to Insulin Release in vitro  
 Abstract    The mutual enhancement of the effect of insulin release by glucose and amino acids is not clearly understood. Present in vitro studies with isolated rat islets were undertaken to elaborate the role of amino acids on insulin release, particularly their interaction with glucose as well as among each other, which has been reported to lead to synergism in the hum an subjects. In the presence of 8.3 mM glucose, both arginine, as well as, leucine potentiated the effect of glucose which increased progressively with the increasing concentrations of the amino acid. This effect of arginine was not synergistic in nature because arginine did not stimulate insulin release in the absence of glucose. The effect of glucose and leucine was found to be additive and not synergistic. No synergism was exhibited by any o f the am ino acid pairs tested in the present study. Thus both phenylalanine and lysine did not potentiate the effect o f either arginine or leucine. Arginine showed a mild, but significant potentiating effect on leucine-stimulated insulin release. It is suggested that synergism between glucose and amino acids and between certain am ino acid pairs reported in m an may not be due to the direct effects of these stimuli on the beta cells, but some other factors in vivo may be involved. 
  Reference    Z. Naturforsch. 35c, 72—7 (1980); received September 3 1979 
  Published    1980 
  Keywords    Insulin Release, Glucose, Amino Acids, Synergism, Rat Islets 
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 TEI-XML for    default:Reihe_C/35/ZNC-1980-35c-0072.pdf 
 Identifier    ZNC-1980-35c-0072 
 Volume    35 
5Author    Ricardo FerreiraRequires cookie*
 Title    Why 43 Codons?  
 Abstract    An attempt is made to answer the question posed by the title of this paper. First we show that in primitive self-replicating oligoribotide systems, selection depended from the very start on the existence of 4 kinds of ribotides, forming 2 complementary pairs. Further selection required that the condensation reactions involving the two last positions o f the 3'-end of a growing oligoribotide fragment and the first position of the 5 '-end of another fragment were catalyzed by randomly synthesized peptides. This established a codon -amino acid concen­ tration correlation and clinched triplet segments as the basis o f the translation process. Finally, physical arguments are given to show that the monochirality of the ribotides arose from stereochemical reasons, as firstly described by Wald, but that of the amino acids is the result of natural selection acting during the peptide-assisted stage o f oligoribotide growth. 
  Reference    Z. Naturforsch. 50c, 148 (1995); received August 8 1994 
  Published    1995 
  Keywords    G enetic Code, Codons, Oligoribotides, Amino Acids, Monochirality 
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 TEI-XML for    default:Reihe_C/50/ZNC-1995-50c-0148.pdf 
 Identifier    ZNC-1995-50c-0148 
 Volume    50 
6Author    Wilhelm Simonis, Johanna Lee-KadenRequires cookie*
 Title    Selektive  
 Abstract    Wirkungen von Lindan (y-l,2,3,4,5,6-Hexachlor-cyclohexan) auf Photosynthese, Aminosäure — Membrantransport und Proteinsynthese bei Anacystis nidulans Selective Effects of Lindane (7-1,2,3,4,5,6 Hexachlorocyclohexane) on Photosynthesis, M embrane Transport of Amino Acids and Protein Synthesis in Anacystis nidulans Effects of the chlorinated hydrocarbon insecticide Lindane on membrane transport of two neu­ trale amino acids in the Cyanobacterium Anacystis nidulans (Synechococcus AN) were measured. In white light the L-Leucine incorporation into the protein fraction was inhibited, increasing with time. After 30 minutes the degree of inhibition was the same as the effect of DCMU (5X 10-6 m) on L-Leucine incorporation. 14C 02-fixation was also reduced at this time. At 717 nm, which en­ ables PS I activity allone, no inhibition was observed. The light energy dependent membrane transport itself of L-leucine in presence of CAM and of the non-metabolisable a-AIB in white light and in monochromatic light of 630 nm and of 717 nm were not influenced by Lindane. The different sites of Lindane action are discussed. It is assumed that in 30 minutes chiefly photo­ synthesis (PS II and C 02-fixation) is affected by Lindane, resulting in a suppression of protein synthesis caused by a depletion of intermediates of C 02-fixation. 
  Reference    Z. Naturforsch. 34c, 1062—1065 (1979); eingegangen am 12. Juni 1979 
  Published    1979 
  Keywords    Anacystis nidulans, Lindane Effects, Amino Acids, Membrane Transport, Photosynthesis 
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 TEI-XML for    default:Reihe_C/34/ZNC-1979-34c-1062.pdf 
 Identifier    ZNC-1979-34c-1062 
 Volume    34 
7Author    G. Gundlach, E. L. Sattler, U. W. AgenbachRequires cookie*
 Title    Gewinnung trägerfreier Syntheseprodukte in bestrahltem Valin durch heiße 11C-Atome aus (y, n)-Kernreaktionen Carrierfree Synthesis Products from Irradiated Valine by Means of Hot nC-Atoms of Giant Resonance Reaction  
 Abstract    The hot uC-atom derived from (y, n)-nuclear reaction of the 40 MeV-Bremsstrahlung of a electron linear accelerator may react with valine irradiated. Besides retention-labelling of valine new products which are essentially carrierfree may be produced. By this means leucine has been separated using HPLC and identified by electrophoresis in amounts of 25 MBq labelled com­ pound. 
  Reference    Z. Naturforsch. 40c, 351—355 (1985); eingegangen am 29. November 1984 
  Published    1985 
  Keywords    zugeeignet Carrierfree Synthesis, Amino Acids, Valine, Leucine (y, n)-Nuclear Reaction 
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 TEI-XML for    default:Reihe_C/40/ZNC-1985-40c-0351.pdf 
 Identifier    ZNC-1985-40c-0351 
 Volume    40 
8Author    Willi Schuh, Heinrich Puff, ErwinA. Galinski, HansG. TrüperRequires cookie*
 Title    Die Kristallstruktur des Ectoin, einer neuen osmoregulatorisch wirksamen Aminosäure The Crystal Structure of Ectoine, a Novel Amino Acid of Potential Osmoregulatory Function  
 Abstract    The crystal structure of ectoine (l,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid) iso­ lated from the extremely halophilic phototrophic bacterium Ectothiorhodospira halochloris was determined by X-ray analysis. This novel cyclic amino acid forms zwitterionic molecules with delocalized ^-bonding in the N-C-N group of the hydrated pyrimidine ring. The molecules are connected by N -H ...O hydrogen bonds. The excellent solubility of ectoine in water can be explained by its structural features which also account for its function as a compatible solute in halophilic bacteria. 
  Reference    Z. Naturforsch. 40c, 780—784 (1985); received July 8/August 9 1985 
  Published    1985 
  Keywords    gewidmet X-Ray Structure Analysis, Ectoine, Amino Acid, Compatible Solute, Osmoregulation 
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 TEI-XML for    default:Reihe_C/40/ZNC-1985-40c-0780.pdf 
 Identifier    ZNC-1985-40c-0780 
 Volume    40 
9Author    Siegfried Huneck, Andrea Porzel, Jürgen Schmidt, Gerhard FollmannRequires cookie*
 Title    Hypothallin, ein weiterer Vertreter eines Aminosäure-aminoalkohol-esters aus der Krustenflechte Schismatomma hypothallinum Hypothallin, a Further Representative of an Amino Acid Amino Alcohol Ester from the Crustose Lichen Schismatomma hypothallinum  
 Abstract    Hypothallin, a metabolite of the lichen Schismatomma hypothallinum (Lecanactidaceae, Opegraphales) has been structurally elucidated as (-)-N-benzoyl-L-phenylalaninyl-N'-benzoyl-L-leucinate by N M R and MS and by synthesis. 
  Reference    Z. Naturforsch. 47c, 785—790 (1992); eingegangen am 25. August 1992 
  Published    1992 
  Keywords    Lichens, Schismatomma hypothallinum, Hypothallin, Amino Acid, Amino Alcohol Ester 
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 TEI-XML for    default:Reihe_C/47/ZNC-1992-47c-0785.pdf 
 Identifier    ZNC-1992-47c-0785 
 Volume    47 
10Author    IvankaG. Stankova3, M. Ario, F. Simeonovb, Vera Maximova0, AngelS. Galabov0, EvgenyV. GolovinskydRequires cookie*
 Title    Synthesis and Anti-Virus Activity of Some Nucleosides Analogues  
 Abstract    New 3'-, 5'-, 5-bromo-2'-deoxyuridine (3 a -g) and 3'-, 5'-thymidine (4 a -i) analogues with amino acid and peptide residues were synthesized and evaluated for antiviral activity. The influence of long peptide chains, essential amino acids and the effect of this structural modifi­ cation on the antiviral activity has been also reported. Three 5-bromo-2'-deoxyuridine derivatives containing glycyl-, glycyl-glycyl-and glycyl-gly-cyl-glycyl-residues (3a, 3b, 3c) showed a strong activity against the herpes virus PsRV and a moderate one vs. HSV-1. The corresponding thymidine analogues were considerably less effective, and only com­ pounds 4d and 4h showed a borderline effect against PsRV. 
  Reference    Z. Naturforsch. 54c, 75—83 (1999); received August lO/October 20 1998 
  Published    1999 
  Keywords    5-Bromo-2'-Deoxyuridine, Thymidine, Amino Acids, Peptides, Antiherpes Activity 
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 TEI-XML for    default:Reihe_C/54/ZNC-1999-54c-0075.pdf 
 Identifier    ZNC-1999-54c-0075 
 Volume    54 
11Author    Requires cookie*
 Title    Okan Gurel  
 Abstract    It is proposed that the biological communication is a language process with the basic word structure formed as a hexagonal neighborhood on the a-helix region of protein molecules. 
  Reference    (Z. Naturforsch. 30c, 843 [1975]; received) 
  Published    1975 
  Keywords    ) a-Helix, Amino Acids, Proteins, Hexagonal Neighborhood, Biological Communication 
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 TEI-XML for    default:Reihe_C/30/ZNC-1975-30c-0843_n.pdf 
 Identifier    ZNC-1975-30c-0843_n 
 Volume    30