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1988 (1)
1985 (1)
1Author    R. J. Youngman, G.R W Agner, F. W. Kühne, E. F. ElstnerRequires cookie*
 Title    Biochemical Oxygen Activation as the Basis for the Physiological Action of Tetrachlorodecaoxide (TCDO)  
 Abstract    Oxidation of methionine, 4-(methylthio)-2-oxobutyric acid (KMB), or 1-aminocyclopropane carbonic acid (ACC) are indicator reactions for activated oxygen species such as singlet oxygen ('02), OH'-radical like oxidants, superoxide anion (02'"), hydrogen peroxide (H 20 2) or activated hemo-iron complexes like peroxidase-or catalase-"compound I". Methionine is oxidized by OH' as well as by '02 forming ethylene, but not by tetrachloro-decaoxygen complex (TCDO) in the absence or presence of catalytic hemoproteins such as peroxidase, hemoglobin or myoglobin. Both KMB and ACC are oxidized by TCDO under the catalysis of the above hemo-proteins where neither catalase nor superoxide dismutase are inhibitors. TCDO hemo-protein complex is an oxidant with similar properties as peroxidase-compound I and can clearly be differentiated from 02'~, H20 2, OH' and '02. 
  Reference    Z. Naturforsch. 40c, 409—414 (1985); received March 18 1985 
  Published    1985 
  Keywords    Tetrachlorodecaoxide, OxoferinR, Activated Oxygen, Heme Catalysis, Wound Healing 
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 TEI-XML for    default:Reihe_C/40/ZNC-1985-40c-0409.pdf 
 Identifier    ZNC-1985-40c-0409 
 Volume    40 
2Author    Heme, ErichF. ElstnerRequires cookie*
 Title    Hämaktivierte Oxidationen mit dem Chlorit-Sauerstoff-Komplex "TCDO" (OXOFERIN®) -eine Übersicht  
 Abstract    Several chlorooxygen compounds, hydrogen peroxide and reducing molecules in the presence of chelated iron (Fenton systems) are oxidants of biological relevance. These compounds are either produced in living tissues or are in use as desinfectants or drugs. Tetrachlorodecaoxide as the active principle in the drug OXOFËRIN® can be differentiated from the above mentioned oxi-dants by means of simple biochemical test systems where different activators and detector mole-cules are used. 
  Reference    Z. Naturforsch. 43c, 893—902 (1988); received March 4 1988 
  Published    1988 
  Keywords    Chlorooxygen Compounds, Activated Oxygen, Hydrogen Peroxide, Biological Oxidants, Fenton Oxidants 
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 TEI-XML for    default:Reihe_C/43/ZNC-1988-43c-0893.pdf 
 Identifier    ZNC-1988-43c-0893 
 Volume    43