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1978 (1)
1Author    Georg SchmettererRequires cookie*
 Title    ATP Dependent Uptake of Zinc by Human Erythrocyte Ghosts  
 Abstract    The energy dependence of Zn2+ accumulation by human erythrocytes was studied by preparing resealed ghosts loaded with ATP or AMP. Uptake of Zn2+ was followed by radioactivity or atomic absorption spectroscopy measurements. Zn2+ taken up is not adsorbed by the mem­ brane but transported into the ghosts. Ghosts containing ATP took up more Zn2+ than those con­ taining AMP. The effect is not specific for ATP, however, GTP and CTP showing the same in­ creased uptake. Zn2+ uptake by ATP ghosts can be further drastically enhanced by addition of Cu2+ . Therefore, in spite of the enhancement of Zn2+ uptake by ATP, Zn2+ seems to be accumulated by a passive mechanism even when the ghosts contain ATP. The accumulation is probably brought about by binding of Zn2+ to substances inside the ghosts. 
  Reference    Z. Naturforsch. 33c, 210 (1978); received January 23/February 16 1978 
  Published    1978 
  Keywords    Zinc Accumulation, Zinc Transport, ATP Dependent Transport, Erythrocyte Ghosts 
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 TEI-XML for    default:Reihe_C/33/ZNC-1978-33c-0210.pdf 
 Identifier    ZNC-1978-33c-0210 
 Volume    33