| | 201 | Author
| M. Veith, 0. Reckten | Requires cookie* | | | Title
| Cyclische Diazastannylene, XVIII [1] Zur Frage der Bindungsbeschreibung in Polyedern des Typs Sn4X3Y: Die Kristall-und Molekülstrukturen von Sn4(N Bu)4 und Sn4(N'Bu)30 Cyclic Diazastannylenes, XVIII [1] Bonding Description in Polyhedra of the Sn4X3Y-Type: The Crystal and Molecular Structures of Sn4(N'Bu)4 and Sn4(N<Bu)30  | | | | Abstract
| Crystals of Sn4(N J Bu)4 (1) are monoclinic, space group P2i/c, with cell constants a = 1038.9(4), b = 1468.3(5), c = 1698.8(5) pm, ß = 91.6(1)° and Z = 4, while those of Sn4(N i Bu)30 (2) are triclinic, space group P I, with dimensions a = 1293.0(5), b = 1027.1(5), c = 1716.7(9) pm, a = 90.9(1), ß = 102.5(1), y = 107.0(1)° and Z = 4. The molecules 1 are held together by van-der-Waals forces, whereas two molecules 2 interact in the crystal by weak 0->-Sn donor bonds (290-332 pm) forming dimers. The outstanding structural elements of 1 and 2 are the Sn4N4 and Sn4N30 polyhedra, which can be described by two interpenetrating tetrahedra of tin atoms and of nitrogen or nitrogen and oxygen atoms forming a distorted cube, which approaches "43 m symmetry in the case of 1 and 3m for 2. Characteristic distances are in 1: Sn-N 220.2 pm, in 2: Sn-N 221.3 pm and Sn-0 213.2 pm. An almost ionic bonding model and two covalent models are discussed on the basis of the structural data including Sn4(N i Bu)3OAlMe3. | | | |
Reference
| Z. Naturforsch. 38b, 1054—1061 (1983); eingegangen am 9. Juni 1983 | | | |
Published
| 1983 | | | |
Keywords
| gewidmet Crystal Structure, Molecular Structure, Cubane-Like Polycycles, Bonding Description, X-Ray | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1054.pdf | | | | Identifier
| ZNB-1983-38b-1054 | | | | Volume
| 38 | |
| 202 | Author
| Manfred Weidenbruch, Hermann Flott, Bernd Ralle, Karl Peters, Hans Georg Von Schnering | Requires cookie* | | | Title
| | | | | Abstract
| Tri-iertf-butylisopropylsilane, l,2-Bis(tri-fer£-butylsilyl) Substituted Ethanes and Ethenes, Steric Hindrance, X-Ray Reaction of tri-ter£-butyl(dihalomethyl)silanes (halo = chloro, bromo) with organolithium compounds, by lithium/halogen or lithium/hydrogen exchange, leads to the corresponding carbenoids which by lithium halide elimination could give the carbenes (£-C4H<))3SiCX. Further intermolecular or intramolecular reaction of these reactive intermediates provides a variety of crowded molecules including alkyltri-iertf-butylsilanes, l,2-bis(tri-ter<-butyl-silyl)-substituted ethanes and ethenes and ring substituted 1,2-di-ter<-butyl -1 -silacyclo -butanes. An X-ray structure determination of (E)-l,2-bis(tri-£er£-butylsilyl)-l,2-dichloro-ethene reveals neither a twisting nor an elongation of the CC double bond, but the C —C-Si bond angles exhibit rather unusual values (up to 137.7°) and the Si-C (sp 2) bonds are as long as 195 pm. | | | |
Reference
| Z. Naturforsch. 38b, 1062—1068 (1983); eingegangen am 5. Mai/6. Juni 1983 | | | |
Published
| 1983 | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1062.pdf | | | | Identifier
| ZNB-1983-38b-1062 | | | | Volume
| 38 | |
| 203 | Author
| M. Bobadilla, M. Morán | Requires cookie* | | | Title
| Oxidative Addition of Pseudohalogen to [P(OPh)3]4Ni | | | | Abstract
| The title compound reacts with cyanogen halides, XCN (X = Br or I) to give the com-plexes L2(X)(CN)Ni (L = P(OPh)3, X = Br or I). The oxidative addition of (SCN)2 and (SeCN)2 to the same compound results in the formation of L2Ni(XCN)2 (X = S or Se). All the complexes have been characterized by elemental analysis, and IR, iH NMR and electronic spectra. | | | |
Reference
| Z. Naturforsch. 38b, 1069—1071 (1983); received May 13 1983 | | | |
Published
| 1983 | | | |
Keywords
| Pseudohalogens, IR Spectra, Nickel | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1069.pdf | | | | Identifier
| ZNB-1983-38b-1069 | | | | Volume
| 38 | |
| 205 | Author
| Wieland Krüger, Michael Sell, Reinhard Schmutzler | Requires cookie* | | | Title
| A New Synthesis of Organodifluorophosphites and their Reactions with Platinum(II) Complexes | | | | Abstract
| Alkyldifluorophosphites, ROPF2 (R = ^-substituted benzyl group, neopentyl, 1-ada-mantyl) have been obtained by a new method, involving reaction of the appropriate alkyl trimethylsilylether, ROSiMe3 with chlorodifluorophosphine, PF2C1. Reactions of these difluorophosphites with platinum(II) complexes of the type [LaPtCla] (L = PEt3, PPI13) led to products such as irans-[L2PtCl(POF2)] and {[p-XC6H4CH2PPh3]+}2[Pt(POF2)4] 2 -, (X = H, Me, Cl, N02). The ease of carbon-oxygen cleavage in ROPF2 is characteristically related to the nature of the leaving group, R. | | | |
Reference
| Z. Naturforsch. 38b, 1074—1080 (1983); received April 25 1983 | | | |
Published
| 1983 | | | |
Keywords
| Organodifluorophosphites, Difluorophosphonate Complexes, Platinum, NMR Spectra | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1074.pdf | | | | Identifier
| ZNB-1983-38b-1074 | | | | Volume
| 38 | |
| 206 | Author
| Gerhard Thiel, Wolfgang Beck | Requires cookie* | | | Title
| Metallkomplexe mit biologisch wichtigen Liganden, XXVII [1] PalJadium(II)-und Platin(II)-Komplexe mit Aminomonosacchariden Metal Complexes with Biological Important Ligands, XXVII [1] Palladium(II) and Platinum(II) Complexes with Aminomonosaccharides Aminomonosaccharides, Palladium(II) Complexes, Platinum(II) Complexes A series of dihalo palladium and platinum complexes X2PtL2 (X = Cl, I) with amino- sugars L = 2-amino-2-deoxy-l,3,4,6-tetra-0-acetyl-/?-D-glucopyranose, l-O-methyl-2- amino-2-deoxy-4,6-0-benzyliden-a,/S-D-glucopyranoside, l-0-methyl-2-amino-2-deoxy- a,/S-D-glucopyranoside, 6-amino-6-deoxy-1,2:3,4-di -O-isopropyliden-a | | | | Abstract
| D-galactopyranose has been prepared and characterized by their IR, X H and 13 C NMR spectra. Mono-saccharides and aminomonosaccharides have been attached to the complex via the carboxy group of a-amino acid Pt 11 complexes to give esters or amides with the mono-saccharides as the alcohol or amine components, respectively. | | | |
Reference
| Z. Naturforsch. 38b, 1081—1093 (1983); eingegangen am 9. Mai 1983 | | | |
Published
| 1983 | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1081.pdf | | | | Identifier
| ZNB-1983-38b-1081 | | | | Volume
| 38 | |
| 207 | Author
| Günter Schmid, Uwe Höhner, Detlef Kampmann | Requires cookie* | | | Title
| Azaborolinyl-Komplexe, XII [1] Gemischte ^ 4 -1.2-Azaborolin-^ 5 -cyclopentadienyl-und ^ 5 -1.2-Azaborolinyl-^ 5 -cyclopentadienyl-Cobalt-Sandwich-Komplexe Azaborolinyl Complexes, XII [1] Mixed ^ 4 -l,2-Azaboroline-7j 5 -cyclopentadienyl-, and ^ 5 -l,2-Azaborolinyl-^ 5 -cyclopentadienyl Cobalt Sandwich Complexes | | | | Abstract
| ?j 4 -Azaboroline, r/ 5 -Azaborolinyl, Cyclopentadienyl, Mixed Cobalt Sandwiches Neutral l-ter^-butyl-2-methyl-zl 3 -l,2-azaboroline and 2-methyl-1-trimethylsilyl-./] 3 -1,2-azaboroline act as 4tz electron donors in the mixed sandwich complexes l-ierf-butyl-2-methyl-^ 4 -l,2-azaboroline-^ 5 -cyclopentadienyl cobalt (1) and 2-methyl-1-trimethylsilyl-?7 4 -l,2-azaboroline-?7 5 -cyclopentadienyl cobalt (2), respectively. They are formed by the reaction of (C5Hs)Co(C2H4)2 with the free ligands without any solvent and are isolated as green oily liquids. 1 and 2 can be transformed into mixed sandwich complexes with rj 5 -1,2-azaborolinyl ring ligands by loss of a hydrogen atom of the CH2 group. This occurs at room temperature to give l-<er<-butyl-2-methyl-ry 5 -l ,2-azaborolinyl-r/ 5 -cyclopentadienyl cobalt (3) and 2-methyl-1-trimethylsilyl-^ 5 -l,2-azaborolmyl-^ 5 -cyclopentadienyl cobalt (4) in low yields. Mass, 1 H, and U B NMR spectra are discussed. | | | |
Reference
| Z. Naturforsch. 38b, 1094—1097 (1983); eingegangen am 25. April/6. Juni 1983 | | | |
Published
| 1983 | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1094.pdf | | | | Identifier
| ZNB-1983-38b-1094 | | | | Volume
| 38 | |
| 209 | Author
| D. Bryce-Smith, A. Gilbert, N. Al-Jalal, R. R. Deshpande, J. Grzonka, M. A. Hems, P. Yianni | Requires cookie* | | | Title
| Acid and Polarity Effects in Benzene Photoreactions with Alkenes and Alkynes | | | | Abstract
| The effects of polar solvents and proton donors on various photoreactions of the benzene ring with electron-acceptor alkenes and alkynes are described and discussed in relation to the various electronic excitation mechanisms involved. Proton donors prove valuable as mechanistic probes for polar intermediates in such processes, and can in some systems both initiate and divert reaction pathways. In 1970 we observed that the course of the photo-chemical cycloadditions of certain ethylenic and acetylenic compounds to benzene, earlier reported by us [1, 2], was profoundly altered in the presence of proton donors, leading to a type of photochemical Friedel-Crafts reaction [3]. Since then, we have described, mostly in preliminary form, numerous further examples of acid catalysis in the photo-reactions of benzene, viz. with amines [4], ethers [5], a ketone [6], a carboxylic acid [6], and hexa-fluorobenzene [7]. Our objective in this present paper is to bring together the previous preliminary reports on acid catalysis in the photoreactions of ethylenic and acetylenic compounds with benzene in conjunction with unpublished recent findings, and to provide a mechanistic rationale together with relevant experimental details. But before we proceed to consider the acid-cata-lysed processes, it is desirable to summarise the main types of reaction that have been shown to occur in the absence of acids. Ethylenes and/or acetylenes photoadd to benzene in the following four main ways: (a) ortho cycloaddition; (b) meto-cycloaddi-tion; (c) £>ara-cycloaddition; and (d) para-ene addi-tion [8, 9]. The mode of addition varies with the addend, and in some cases more than one pathway may be followed. In the case of (a), the adducts (1) of ethylenes may be obtained as such when the ethylenic addend is not a strong thermal dienophile, e.g. acrylonitrile [10], 2,3-dihydropyran [11]. When it is a strong dienophile, as in the case of maleic * Reprint requests to Prof. D. Bryce-Smith. 0340-5087/83/0900-1101/$ 01.00/0 anhydride and certain maleimides, a second mole-cule may add thermally to give the remarkably | | | |
Reference
| Z. Naturforsch. 38b, 1101—1112 (1983); received May 2 1983 | | | |
Published
| 1983 | | | |
Keywords
| Photoreactions, Benzene, Alkenes, Alkynes, Acid Effects | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1101.pdf | | | | Identifier
| ZNB-1983-38b-1101 | | | | Volume
| 38 | |
| 210 | Author
| Klaus Jonas, Volker Wiskamp, Professor Karl | Requires cookie* | | | Title
| Olefin-, Aromaten-und Allylkomplexe des Vanadiums aus Vanadocen [1] Olefine, Arene, and Allyl Complexes of Vanadium from Vanadocene [1] | | | | Abstract
| Vanadocene (Cp2V) was reduced with potassium metal in tetrahydrofuran (THF) to give a 1:1 adduct K[Cp2V] which has been isolated as [K(THF)(Et20)][Cp2V]. The reactions of this compound with various molecules (L) capable of functioning as ligands were investigated. They cause the liberation of KCp and the formation of several new organovanadium compounds. The products of these reactions were: [K(THF)2 5][CpVCsHi2] for L = butadiene (C4H6), [K(THF)i.5][CpVC6H5P(C6H5)2] for L = P(C6H5)3, CpV(C4H6)P(CH3)3 for L = mixture of C4H6 and P(CH3)3. Vanadocene was reacted with allyllithium to yield LiCp and [LiTMEDA][CpV(C3H5)2] (TMEDA =: (CH3)2NCH2CH2N(CH3)2), which was transformed via allylbromide to CpV(C3Hö)2. Structures and reactivities of these new organovanadium complexes are discussed. I. Einführung Unlängst berichteten wir in Übersichtsaufsätzen [2, 3] zusammenfassend über eine von uns ent-wickelte Synthesemethode, durch die reaktive Über-gangsmetall-Olefin-und Alkalimetall-Übergangs-metall-Olefin-Komplexe des Nickels, Cobalts und Eisens auf einfache Weise zugänglich geworden sind, z.B. mit Ethen als Olefin: Et20 Cp2Co + K + 2 C2H4 • CpCo(C2H4)2 + KCp THF Cp2Co + 3K + 4C2H4 • K[Co(C2H4)4] + 2 KCp THF Cp2Fe + 2 Li + 2 C2H4 Li[CpFe(C2H4)2] + LiCp Wir haben nun überprüft, ob sich dieses Synthese-prinzip, das auf der reduktiven Ablösung der Cp-Ringe von den entsprechenden Metallocenen mittels Alkalimetall in Gegenwart von Olefinen beruht, auch auf das elektronenärmere Vanadocen über-tragen läßt. Überdies war zu klären, ob neben Olefinen auch andere Komplexbildner wie Kohlen-monoxid oder Phosphane oder gar Mischungen von Komplexbildnern eingesetzt werden können. Hier-über sowie über einen zweiten Synthese weg, der | | | |
Reference
| Z. Naturforsch. 38b, 1113—1121 (1983); eingegangen am 7. März 1983 | | | |
Published
| 1983 | | | |
Keywords
| Vanadium, Potassium, Vanadocene, Allyllithium, Olefines | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1113.pdf | | | | Identifier
| ZNB-1983-38b-1113 | | | | Volume
| 38 | |
| 211 | Author
| KurtH. Pilgram, LairdH. Gale, GlennE. Pollard | Requires cookie* | | | Title
| a-hydroxyphostones | | | | Abstract
| The addition-cyclocondensation reactions of three /?-hydroxyketones with four dialkyl phosphites gave 2-alkoxy-3-hydroxy-l,2-oxaphospholane-2-oxides ("a-hydroxyphosto-nes") (7), in moderate yields. In the solid state and in solution, these compounds exist as dimers with hydrogen bonding between the hydroxyl group and the phosphoryl oxygen atom of an adjacent molecule. The crystal and molecular structure of 3-hydroxy-2-methoxy-3,5,5-trimethyl-l,2-oxaphospholane-2-oxide (7 a) has been determined by single-crystal X-ray crystallography: C7H15O4P, monoclinic space group P2-l/n, cell dimensions a = 8.087(1) Ä, b = 13.386(2) A, c = 9.306(1) A, V = 1007.4 Ä 3 , Z = 4, final R = 0.052. The five-membered ring is puckered, with the carbon bearing the OH and CH3 groups lying out of the plane of the remaining four atoms in the ring. The doubly bonded oxygen attached to the phosphorus atom and the hydroxyl oxygen are in a cis-relationship. The 0(l)-0(4) intermolecular bond distance of 2.75 Ä suggests hydrogen bonding. The 0(1)-H(1) intermolecular bond distance of 1.97 Ä is consistent with this conclusion. Thorough synthetic studies have been carried out on intramolecular esters of 3-hydroxyalkane (and alkene) phosphonic and phosphinic acids (phosto-nes [1]). For example, dehydration of 3-hydroxy-alkanephosphonic acids gave phostones of general structure 1 [2] (Table I). Similar phostones, 2 and 3, were obtained from the reactions of 1,3-dihalo-alkanes with phosphonites and phosphinites, re-spectively [3]. At elevated temperature, 3-bromo-alkanephosphonates are converted into phostones 4 [4]. Acyl-lactone rearrangement of a-acetyl-a-diethoxyphosphonylbutyrolactone gave 5 [5]. Unsaturated phostones (8) are obtained by dehydration of the corresponding (3-hydroxy-3-phenyl-prop-2-enyl)phosphonic acids [6]. 3-Hy-droxypropenylphosphonates, prepared by catalytic reduction of 3-hydroxy-l-propynyl-phosphonates, cyclocondense to 9 having potent Cholinesterase inhibitory activity [7]. The reaction of dialkyl 1,2-alkadienylphosphonates with halogens [8-10] and sulfenyl chlorides [12] gave 10. In the reaction of 3-methyl-l,2-butadienephos-phonyl di chloride with halogens, unsaturated tetra-halophostones (11), are formed [13]. The chlorina-tion of 2-methyl-2,3,5-hexatriene-4-phosphonyl di-chloride proceeds similarly in the direction of cyclo-dechlorination to form 12 [14]. | | | |
Reference
| Z. Naturforsch. 38b, 1122—1129 (1983); received May 6 1983 | | | |
Published
| 1983 | | | |
Keywords
| X-Ray, Stereochemistry, Hydrogen Bonding, Dimerization | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1122.pdf | | | | Identifier
| ZNB-1983-38b-1122 | | | | Volume
| 38 | |
| 212 | Author
| Helmut Vogler | Requires cookie* | | | Title
| Theoretical Study of the Orientation Dependence of Charge-Transfer Excitations in Quinhydrones | | | | Abstract
| The two longest wavelength electronic transitions of the quinhydrones 1 and the dependence of transition energies and intensities on the mutual orientation of hydro-quinone and £>-benzoquinone is studied within semiempirical JI-theory. The results are in good agreement with the experimental UV-VIS spectra of closely related cyclophane-quinhydrones. The study is extended to the yet unknown quadruple-layered systems 2 which consist of two quinhydrone moieties. The UV-VIS spectra of the diastereomeric quin-hydrones of the [2.2]-and [3.3]paracyclophane series [1, 2] demonstrate that the charge-transfer (CT) interaction depends significantly on the mutual orientation of the hydroquinone (H) and -benzo-quinone (Q) moiety. This could be expected in principle considering Mulliken's theory [3]. A first qualitative interpretation of the longest wavelength part of the electronic spectra of the intermolecular quinhydrones la and lb (cf. Fig. 1) was given with 2a 2b the aid of simple Hückel theory [4]. An extension of that work seems to be appropriate since there the magnitude of the transanular interaction was treated as a further parameter and electron inter-action was not explicitely taken into account in a Hückel approach although it might be crucial for a proper description of electronic excitations. There-fore we present in this communication a study of the lower excited singlet states of the quinhydrones 1(a) (cf. Fig. 1) as a function of the geometry | | | |
Reference
| Z. Naturforsch. 38b, 1130—1135 (1983); received April 19 1983 | | | |
Published
| 1983 | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1130.pdf | | | | Identifier
| ZNB-1983-38b-1130 | | | | Volume
| 38 | |
| 214 | Author
| Maria Konieczny, CarlA. Olson, PeterL. Gutierrez, George Sosnovsky | Requires cookie* | | | Title
| In the Search for New Anticancer Drugs, IV+ Antitumor Activity of Seleno-TEPA | | | | Abstract
| In order to test the effect of selenium on the anticancer activity of alkylating drugs, Seleno-TEPA (4), the selenium analog of the clinically used Thio-TEPA (1) was tested in vivo against the lymphocytic P 388 and lymphoid L1210 murine leukemias. Compound 4 is more active against P 388 leukemia than against L1210, and appears to be active over a narrower concentration range than Thio-TEPA (1). Compound 4 is less active against P 388 leukemia than 1, as evidenced by the T/C values of 164 for 4 and 239 for 1 at a dose of 4.2 mg/kg. The activity of 4 was also evaluated on the HL60 and K 562 human cell lines. Under the conditions of the cell colony assay technique, Seleno-TEPA (4) is less effective than Thio-TEPA (1). | | | |
Reference
| Z. Naturforsch. 38b, 1138—1141 (1983); received August 30 1982/March 14 1983 | | | |
Published
| 1983 | | | |
Keywords
| Thio-TEPA, Selenium, Seleno-TEPA, Anticancer Drugs | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1138.pdf | | | | Identifier
| ZNB-1983-38b-1138 | | | | Volume
| 38 | |
| 215 | Author
| Maria Konieczny, CarlA. Olson, PeterL. Gutierrez, George Sosnovsky | Requires cookie* | | | Title
| In the Search for New Anticancer Drugs, V+ Study of the Binding of Spin-Labeled Thio-TEPA to Cells | | | | Abstract
| The spin labeled analog, SL-O-TT (2), of Thio-TEPA (1) inhibits (£N) 3 PIS) R0P(S)(N3) 2 the incorporation of 3 H-thymidine by 50% (IC50) at a dose of 2.6 X 10~ 4 M in L 1210 and at a dose of 6 X 10~ 4 M in P 388 murine leukemias. On the basis of cell fractionation studies, compound 2 was found to bind about equally to the cell nuclei, microsomes, and mito-chondria. ESR experiments indicate different degrees of immobilization of the label in various fractions. The efficiency of binding of 2 to cells appears to be at least 6 %. | | | |
Reference
| Z. Naturforsch. 38b, 1142—1145 (1983); received August 30/December 24 1982 | | | |
Published
| 1983 | | | |
Keywords
| Anticancer Drugs, Nitroxyl Label, Spin Labeled Thio-TEPA, ESR | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1142.pdf | | | | Identifier
| ZNB-1983-38b-1142 | | | | Volume
| 38 | |
| 216 | Author
| George Sosnovsky, BuddhaD. Paul | Requires cookie* | | | Title
| In the Search for New Anticancer Drugs, VI+ Structural Modifications of Cyclophosphamide | | | | Abstract
| Taking into consideration the known mechanism of the drug action of cyclophosphamide (1), several analogs and related compounds o, 6, 7, 9, 11, 12 and 27 were synthesized, and tested against lymphocytic leukemia P 388 in mice. CH °N P(0)NM2 (P(0)NM2 F /P(0)NM2 F ,P(0)NM2 I H3cV N 'H h>\ H CH 3 3 CH3 3 CH3 M=CH2CH2CI 5 6 7 (>™2 HO<3-P,O,NM2 / \ R HiC ' w o ' P-NCHUCHUCL 9 11, R = CI 12 27, r^nhch2CH2CH3 Moderate to high activity was found with 5 (T/C X 100 = 243 at a dose of 300 mg/kg), 7 (T/C x 100 = 173 at a dose of 10 mg/kg), 9 (T/C X 100 = 248 at a dose of 100 mg/kg) and 11 (T/C X 100 = 155 at a dose of 55 mg/kg). None of these compounds was found to be more active than 1 (T/C X 100 = 339 at a dose of 65 mg/kg). Although the essential position C4 for the enzymatic activation is completely blocked in 5, the compound posses-ses a high degree of activity. This result justifies a reevaluation of the proposed mechanism of drug action of 1 and its analogs. | | | |
Reference
| Z. Naturforsch. 38b, 1146—1155 (1983); received August 30/December 24 1982 | | | |
Published
| 1983 | | | |
Keywords
| Cyclophosphamide, Drugs, Anticancer, Synthesis, Leukemia P 388 | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1146.pdf | | | | Identifier
| ZNB-1983-38b-1146 | | | | Volume
| 38 | |
| 219 | Author
| ChaitanyaK. Narula, Heinrich Nöth | Requires cookie* | | | Title
| Contribution to the Chemistry of Boron, 136 [1] A Reinvestigation of the Existence of l,3,2-Dioxaborinium(l-|-) Cations l,3,2-Dioxaborinium(l +) Salts, 2-Perchlorato-l-oxa-3-oxonia-2-borato-cyclohexadienes, 2-Triflato-l-oxa-3-oxonia-2-borato-cyclo-hexadienes | | | | Abstract
| It is shown that the previously reported 1,3,2-dioxaborinium salts containing tri-coordinated boron are in fact tetracoordinated coordination compounds. The same holds for the corresponding triflates. | | | |
Reference
| Z. Naturforsch. 38b, 1161—1164 (1983); received July 5 1983 | | | |
Published
| 1983 | | | |
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| default:Reihe_B/38/ZNB-1983-38b-1161.pdf | | | | Identifier
| ZNB-1983-38b-1161 | | | | Volume
| 38 | |
| 220 | Author
| Umlagerung Synthese, Eigenschaften Diphenylphosphinosubstituierter Uracile, Jochen Ellermann, AlfonsA M Demuth | Requires cookie* | | | Title
| Chemie polyfunktioneller Moleküle, 74 [1] [1] Synthesis, Rearrangement and Properties of Diphenylphosphino Substituted Uracils | | | | Abstract
| 5-Bromo-uracil (2) with chloro-diphenylphosphine and triethylamine gives 5-bromo-N(1),N(3)-bis(diphenylphosphino)-uracil (3). In moist acetone, 3 is hydrolyzed to 5-bromo-N(l)-diphenylphosphino-uracil (4). 3 reacts with n-butyllithium under rearrangement and, with HCl, under elimination of a PPh2-group, forms C(5)-diphenylphosphino-uracil (7 a). Recrystallization of 7 a from ethanol yields the ethanol-1:1-adduct 7 b. Heating of 7 a in dimethylsulfoxide with D20 yields the N(l),N(3)-dideutero-C(5)-diphenylphosphino-uracil (7 c). All compounds were characterized by infrared, Raman, iH, 31 P NMR and mass spectra. 7 a shows a very small antitumor activity. | | | |
Reference
| Z. Naturforsch. 38b, 1165—1172 (1983); eingegangen am 19. Mai 1983 | | | |
Published
| 1983 | | | |
Keywords
| Diphenylphosphino Substituted Uracils, Rearrangement, NMR Spectra, Vibrational Spectra, Mass Spectra | | | |
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| | | | | TEI-XML for
| default:Reihe_B/38/ZNB-1983-38b-1165.pdf | | | | Identifier
| ZNB-1983-38b-1165 | | | | Volume
| 38 | |
|
